Epidemiology Of Erectile Dysfunction

Erectile dysfunction in general medicine practice prevalence and clinical correlates. Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. Is erectile dysfunction a marker for cardiovascular disease? In the United states, about 18.

Free testosterone levels vary widely across laboratories and are not uniformly recommended for screening. 5 or 5 mg once daily NA NA NA ($280 for 30 tablets) Vardenafil (Levitra) 10 or 20 mg once daily as needed 60 minutes Four to five hours NA ($465) SURGICAL AND PROCEDURAL THERAPY Second-line treatments for ED include alprostadil (Caverject) and vacuum devices. If a trial of oral therapy and withdrawal of offending medications do not restore erectile function or if a patient has medical or financial contraindications to pharmacologic therapy, most primary care practitioners should consider referring the patient to a specialist for additional evaluation and discussion of alternative treatment options. Severe erectile dysfunction is an independent predictor of poor quality of life and not an indicator for comorbid diseases [2].

Sensitivity analyses using the random-effects model revealed that no single study influenced the overall prevalence of ED in DM patients (Figure 3). Selective serotonin reuptake inhibitor-induced sexual dysfunction. Longitudinal differences in disease specific quality of life in men with erectile dysfunction: Yohimbine for erectile dysfunction: Mulligan T, Frick MF, Zuraw QC, Stemhagen A, McWhirter C. Apart from diseases already mentioned (diabetes, vascular diseases, renal failure) some other disorders are associated with impotence.

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Table 2 shows the prevalence and pattern of ED among respondents. Logistic regression analysis was used to estimate the association between ED and the other variables, adjusting for the simultaneous effect of all the variables in the model. The age group of the respondents was simplified into <40 years old and ≥ 40 years old groups to define age as a dichotomous variable to enable the subsequent analysis. This systematic review included observational studies such as retrospective or prospective cohort studies, and cross-sectional and case-control studies, where ED among DM patients has been reported. In fact, complaints of ED in young men is often underestimated and attributed to transient and self-limiting psychological conditions, such as performance anxiety. (9%) had consensual sex with their wives/partners.

MUSE Study Group. In our Sexual Medicine and Andrology Unit, established in an Endocrinology setting at the University of Florence, medical consultations for younger men are infrequent, with a prevalence of men aged less than 40 years at only 14. This increased to 32% for men aged 65–74 y. Therefore, investigators have evaluated penile cavernous pressure in normotensive animal models. Unconventional CV risk factors, such as impaired erections during masturbation and reduced flaccid acceleration, are interesting parameters to implement in Sexual Medicine context, because they can help fill the gap of information on CV risk, left by the conventional risk factors (the so-called residual risk) (38). Nehra A, Blute ML, Barrett DM, Moreland RB. Erectile dysfunction can cause strain on a couple.

1% of more than 3,000 men complaining of ED. 80 in the environmental dimension. Accurate risk factor identification and characterization are essential for prevention or treatment of erectile dysfunction. The impact of ED on QoL has become very important in the management of ED. ED is a symptom that can provide a chance for both the patients and physicians to unearth the presence of CV risk factors and improve both the quality and length of life of these men. The model of multivariate logistic regression was also applied, adjusting for the OR to control confounding factors as shown in the Table 3. Osman A, Wong JL, Bagge CL, Freedenthal S, Gutierrez PM, Lozano G. Higher rates of reporting, diagnosis, and treatment of ED have been driven by effective treatments, direct to consumer advertising, and screening by health care providers.

  • In some, transplant improves the renal function to the point where the patients erectile function also improves and in others, particularly those men who had received 2 transplants, the erectile function may deteriorate further.
  • Men suffering from hypertension, coronary heart disease, hypercholesterolaemia and diabetes mellitus had a significantly higher rate of erectile dysfunction.

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(1) September 2020 to December 2020 International Index of Erectile Function Consecutive 7 Walle et al. Recently, two studies showed that a single question on ED could be used in epidemiological surveys, but the precise formulation of such a question was not discussed. Moreover, several studies have shown the economic efficiency of treating ED,10,11 that is, treatment for ED can buy much improvement in quality of life for a given budget.

HH also was responsible for checking the reliability of data set as well as performing further data analysis using multivariate models. The instrument used was the International Index of Erectile Function Questionnaire-5 (IIEF-5). Patients should be warned to seek emergency urologic treatment if an erection lasts four hours or longer. (9%) drank less than two cans of beer/day, and 86. Experts recommend that men have a complete medical history and physical examination to determine the cause of ED.

JAMA 1999;281: Prevalence of erectile dysfunction and possible risk factors among men of South-Western Nigeria: Regarding the sampling technique employed, 7 of the studies [17, 21, 41, 42, 46–48] used the consecutive sampling technique to select study participants. Conventional and unconventional cardiovascular risk factors in men with erectile dysfunction. The most plausible explanation calls for the influence of cultural factors. It is important to communicate openly with your partner. Prevalence and medical management of erectile dysfunction in Asia.

  • Stepwise backward method was used in the multivariate regression model.
  • 0% in men aged 40 increasing to 67.
  • Majority (59%) of respondents used intravenous insulin injection medication only.
  • In other cases, the driving force might be psychological.
  • Sexuality is an essential part of life; however, erectile dysfunction (ED) has been one of the most common complaints among men with sexual health issues all over the world.
  • An estimated 10.


However, when considering separately younger and older men, this association was confirmed only in younger ones, and it was still significant after excluding men reporting severe ED during masturbation (35). Crossref | PubMed | Scopus (51) | Google ScholarSee all References. Our study expected to make a considerable contribution to clarification of the role of local health services in meeting the need of community-based sexual health care for men. Respondents completed a self-reported questionnaire. A number of factors were significantly (P < 0. )22 Sullivan M.

The researchers assessed the sexual function of 31,742 men between the ages of 53 and 90, who were enrolled in the Health Professionals Follow-up Study (www. )Kinsey stated that aging is an important risk factor for the development of ED in men. (3 حالة وخيمة). 8% in the 18–30 age group; 44. No reason is immediately apparent for the lower sexual function of Australian-born men compared with their overseas-born counterparts. 58 PDE-5 inhibitors are contraindicated in men using nitroglycerin or other nitrates because of the risk of catastrophic low blood pressure.

Crossref | PubMed | Scopus (27) | Google ScholarSee all References,35x35Morley, J. In a Finnish large-scale national combined face-to-face and questionnaire study,21 996 male respondents (aged 18–74 y) reported an overall 6% prevalence of erection difficulties at least fairly often, while 49% had experienced erection difficulties of any degree during the previous year. 55 Tobacco cessation is highly recommended. We weighted further analyses to reflect the age distribution in the South Australian community; marginal totals thus do not correspond to the totals in Box 1. What are the side effects of long term use of omeprazole? The drug may increase the level of potassium in your blood. Although few studies specifically evaluated the clinical characteristics of ED in younger men, this problem is increasingly frequent. The authors declare that they have no competing interests. In fact, this pathogenetic dichotomy is now obsolete (1,18,19), because it is now known that ED is a multidimensional disorder deriving from the interaction of different components related to organic conditions, relational context and psychological status (20,21). Age and diabeteswere found to be significantly associated withED.

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Unfortunately, additional examination was not possible due to the web-based nature of this study. An integrated approach with vardenafil orodispersible tablet and cognitive behavioral sex therapy for treatment of erectile dysfunction: Feldman HA, Goldstein I, Hatzichristou DG, et al. Is impotence an arterial disorder? Erectile dysfunction occurs at an earlier age in people with diabetes than in the general population [9]. In a cohort of 50 year old men undegoing a nutritional and general health screening, Morley found a 27% incidence of impotence.

The data was entered into Epi data 3. Since this study have used cross-sectional design, we cannot report cause and effect. Effects of medical or surgical castration on erectile function in an animal model.

ED includes dysfunction in erection and penile erectile pain. Optimizing treatment for diabetes mellitus induced erectile dysfunction. Nikolosi et al.

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Int J Impot Res (2020) 14(2): The patients age (mean± S. )The prevalence of ED in this study ranges from 6. 12 It is important to recognize that short-form questionnaire does not evaluate specific areas of the sexual cycle, such as sexual desire, ejaculation, and orgasm; however, it may be useful in discussing ED with patients and evaluating treatment results over time. PDE-5 Inhibitors for Treatment of Erectile Dysfunction Medication* Dosage Minimum time from dosing to sexual activity Elimination half-time Cost for 10 tablets † Avanafil (Stendra) 50, 100, or 200 mg once daily as needed 15 minutes Five to 10 hours NA ($350) Sildenafil (Viagra) 20, 25, 50, or 100 mg once daily as needed 30 minutes Three to five hours $10 ($475) Tadalafil (Cialis) 10 or 20 mg once daily as needed 30 minutes 17. When considering the independent variables in bivariate analyses, as seen as the crude OR results in Table 3, the prevalence of ED in this study showed a statistically significant association with age groups and also with occupation, religion, BMI, alcohol/beer consumption, anxiety, quality of life, average number of hours of sleeping, and consensual sex with their wife/partner during sexual activity. 3% moderate to severe and 2.

  • Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients.
  • 4% in Canada [5] and 63.
  • Impotence and its medical and psychosocial correlates.
  • Nonetheless, 54.
  • Age is one of the primary risk factors of ED.
  • The subgroup analysis in this study showed that the pooled prevalence of ED among diabetic patients in Nigeria was 84.

Relational Component

4% with depression, 81. Of those individual who developed diabetic complication, 72 (60%) of them had developed cardiovascular disorder while only 7 (6%) of them had foot ulcer. In fact, erections during masturbation are far less affected by relational and psychological components than sex-related ones (34). To restore access and understand how to better interact with our site to avoid this in the future, please have your system administrator contact [email protected] In subjects over 80 years of age this figure rose to 60%. Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: After excluding subjects who had prostate surgery (n = 28), the impact of cardiovascular disease or diabetes was greatest for those aged 40 to 49 years, among whom the probability of ED in the absence of cardiovascular disease or diabetes was 31%, with increases to 52% in the presence of cardiovascular disease alone, 57% in the presence of diabetes alone, and 73% when both conditions were present.

The significant disparity in the prevalence might be due to the fact that older men were assessed and the respondents self-rated themselves. When used, the change in air pressure triggers an erection. In a regional Dutch study of 1233 men aged 40–79 y,25 13% reported having difficulties getting an erection. Am J Cardiol 2020;96:

J Clin Endocrinol Metab 1983;56: Many epidemiological studies have demonstrated high prevalence of ED in different parts of the world. Smith and his associates found elevated ED prevalence in all other groups, compared with the white group. Other data have emerged, and we now have a better understanding of the epidemiological profile of ED.

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(Parkinson’s disease, multiple sclerosis). J Diabetes Complications. 18 In the questionnaire, 5% reported more than occasional ED (Table 1), and an additional 15% indicated rare ED. 6%, respectively (Table 1). Why vitamin d might cause erectile dysfunction and how to fix it. The weight attributed to age for estimating the risk in these equations is often so significant that younger men are automatically considered at low risk, irrespective of the other possible risk factors. In an unadjusted analysis, higher mean levels of parathyroid hormone and creatinine were found in patients without ED. The effects of demographic risk factors such as income and education were more apparent in older age groups and were consistent with lower sexual function in lower socioeconomic groups. 001) more common among men with ED (10.


A fasting glucose and plasma lipid profile was obtained for all subjects unless these tests had been completed within the previous 6 months. It was inversely associated with education, physical activity, and alcohol drinking. A larger national study, the National Health and Social Life Survey, looked at sexual function in men and women. Therefore, screening for ED for diabetic patients particularly, for those who aged above 45 years and living with DM for more than 10 years is needed for early detection, treatment and possibly prevention. In most cases, a tentative diagnosis can be established with a complete sexual and medical history, physical examination, and limited or no laboratory testing.

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8% of beer; 16. 1% in South Africa [16], and 67. Men who are taking medications that contain nitrates, such as nitroglycerin, should NOT use these medications. (05) to ED to include age, occupation, religion, disease history, BMI, alcohol consumption, anxiety, quality of life, consensual sex with their wife/partner, and number of hours of sleep per day. For the elderly and for others, ED may occur as a consequence of specific illnesses or of medical treatment for certain illnesses, resulting in fear, loss of image and self-confidence, and depression [1].

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Patient information: TV contributed to the first draft of the manuscript including data collection process management and data analysis. Dehydration and erectile dysfunction: does water help?, in the long term, excessive alcohol consumption also reduces testosterone levels, leading to a loss of libido and is toxic to the testes. Measurement of testosterone in the blood is often done in men with ED, especially with a history of decreased libido or diabetes.

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Montorsi F, Salonia A, Deho' F, Cestari A, Guazzoni G, Rigatti P, et al. The impact of sexually objectifying media exposure on negative body emotions and sexual self-perceptions: Testosterone supplementation for erectile dysfunction: Data from references 20-23. This study was carried out before oral therapy with sildenafil was available. Problems for patients and investigators. Newly diagnosed erectile dysfunction and risk of depression: 4%) and hypercholesterolaemia (78.


There’s also a lot of variation among screening tools and questionnaires used by researchers. Diabetes can cause nerve damage and problems with circulation, both of which can contribute to ED. With respect to the tools used to assess ED in DM patients, 10 studies [21, 41–49] used the International Index of Erectile Function, two [39, 40] used the Sexual Health Inventory for Men, and one study [17] used the Golombok Rust Inventory of Sexual Satisfaction.

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